Plant-based implant nanocoating with anti-inflammatory properties
A recent study has tested the use of nanoparticles derived from plants as a coating for titanium implants. The study was conducted by a team of researchers from various institutions and aimed to find out if this nanocoating could improve osseointegration amongst patients with a high risk of inflammation.
The coating used in this experiment was derived from plant nanoparticles, specifically Rhamnogalacturonan-I (RG-I), a pectic polysaccharide. The researchers hypothesise that this nanoparticle has the potential to improve osseointegration and reduce inflammation caused by bacterial infection. Furthermore, it is useful as a coating as pectins do not degrade in the human body.
The test their hypothesis, the researchers introduced RG-I coated and uncoated titanium surfaces to cells infected with P. gingivalis. The experiment showed promising results. Cells which were cultured on the RG-I nanocoating displayed significantly lower rates of pro-inflammatory cytokine release. This suggests that the nanocoating may an effective means for improving osseointegration in cases involving inflammation.
This study was presented as an e-poster at the 2017 EAO Congress.